This issue picks up right where Amazing Spider-Man #14 left off, with Green Goblin’s face obscured by a safe door. Goblin returns in this issue, but unfortunately for Spider-Man, he attacks right when news arrives that Aunt May is in the hospital
So Spider-Man flees, after a brief fight scene. There will be ramifications of this decision for several issues to come.
Also, check this out:
This is the first time Peter’s spider-sense warns him of a dangerous person who is not actually threatening him–usually, his spider-sense warns of imminent danger.